匹美西林酸及其乙酯：吸收、分布、排泄。
Piromidic acid and its ethylic ester: absorption, distribution, excretion.
作者信息
Rosini S, Benetti D
出版信息
Int Urol Nephrol. 1976;8(1):63-6. doi: 10.1007/BF02081992.
PMID:965200
Abstract
The absorption, distribution and excretion of piromidic acid and its ethyl ester were investigated in the rat. When administered orally the ethyl ester was well absorbed and subsequently hydrolysed, giving much higher blood and tissue concentration than a corresponding dose of the parent compound. The antimicrobial activity of urine and bile samples was also investigated.
摘要
对吡咯米酸及其乙酯在大鼠体内的吸收、分布和排泄进行了研究。口服给药时，乙酯吸收良好，随后水解，其血药浓度和组织浓度比相应剂量的母体化合物高得多。还对尿液和胆汁样本的抗菌活性进行了研究。
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