Popadić A, Abzhanov A, Rusch D, Kaufman T C
Howard Hughes Medical Institute, Department of Biology, Indiana University, Bloomington 47405, USA.
Int J Dev Biol. 1998;42(3):453-61.
Due to the segmental organization of their body plans, arthropods can be considered the paradigmatic modular organisms. In the past two decades, genetic studies of the homeotic (Hox) genes in Drosophila melanogaster have provided initial insight into the molecular mechanisms that govern the establishment of segmental identity. In this review, we will address the question of the possible role of four Hox genes: labial (lab), proboscipedia (pb), Deformed (Dfd), and Sex combs reduced (Scr) in the morphological evolution of arthropods, particularly with respect to the evolution of the head and head structures in insects. Overall, these preliminary studies illustrate the role that some of the Hox genes expressed in the insect head have played in the morphological evolution of hexapods and likely arthropods in general.
由于节肢动物身体结构的分节组织，它们可被视为典型的模块化生物。在过去二十年中，对黑腹果蝇同源异型（Hox）基因的遗传学研究为控制节段身份确立的分子机制提供了初步见解。在本综述中，我们将探讨四个Hox基因：唇（lab）、喙节（pb）、变形（Dfd）和性梳减少（Scr）在节肢动物形态进化中可能发挥的作用，特别是关于昆虫头部和头部结构的进化。总体而言，这些初步研究阐明了在昆虫头部表达的一些Hox基因在六足动物以及可能一般节肢动物的形态进化中所起的作用。
