Kondo T, Fujimura S
Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Nihon Geka Gakkai Zasshi. 1998 May;99(5):303-7.
To date, 162 patients with metastatic pulmonary tumors have undergone surgical treatment in our institute (93 carcinomas, 51 sarcomas, 17 germ cell tumors, 1 melanoma). Of these, 57 and 105 had solitary and multiple lesions, respectively, at their first surgery. Five of 57 patients developed additional lesions later. The incidence of multiple pulmonary metastases was higher in sarcoma than in cancer patients, and the prognosis after surgical treatment was found to be significantly better in cancer than in sarcoma for patients with multiple lesions. However, no significant difference was observed between the survival of those with solitary and multiple lesions. The number of lesions found at surgery was greater than that calculated based on preoperative chest CT scans, and the discrepancy was greater when lesions exceeded 10 in number. However, the increase in the number of metastatic lesions found did not affect the surgical results. There was also no statistical difference in survival between patients with bilateral and unilateral lesions. In contrast, those who underwent complete had a significantly better prognosis than those who underwent incomplete resection at surgery.
迄今为止,我院共有162例转移性肺肿瘤患者接受了手术治疗(93例为癌,51例为肉瘤,17例为生殖细胞肿瘤,1例为黑色素瘤)。其中,首次手术时分别有57例和105例为单发和多发肿瘤。57例单发肿瘤患者中有5例后来出现了新的肿瘤。肉瘤患者发生多发性肺转移的发生率高于癌症患者,对于多发肿瘤患者,手术治疗后癌症患者的预后明显好于肉瘤患者。然而,单发和多发肿瘤患者的生存率之间未观察到显著差异。手术中发现的肿瘤数量多于术前胸部CT扫描计算出的数量,当肿瘤数量超过10个时,差异更大。然而,发现的转移瘤数量增加并未影响手术结果。双侧和单侧肿瘤患者的生存率也无统计学差异。相比之下,手术切除完整的患者预后明显好于手术切除不完整的患者。