Suppr超能文献

基于门诊的老年精神药物处方

Psychotropic prescribing for the elderly in office-based practice.

作者信息

Aparasu R R, Mort J R, Sitzman S

机构信息

College of Pharmacy, South Dakota State University, Brookings, USA.

出版信息

Clin Ther. 1998 May-Jun;20(3):603-16. doi: 10.1016/s0149-2918(98)80069-6.

Abstract

This study employed data from the National Ambulatory Medical Care Survey (NAMCS) 1995 to (1) determine the prevalence of the prescribing of psychotropic drugs for elderly patients by office-based physicians in the United States; (2) estimate the prevalence of the prescribing of potentially inappropriate psychotropic drugs in this patient population; and (3) identify any factors that predict such prescribing. For the purposes of this study, previously developed consensus criteria were adopted defining inappropriate psychotropic drugs as those that should be avoided in the elderly. According to the NAMCS data, psychotropic medications were prescribed in an estimated 12.02 million visits by elderly patients (95% confidence interval [CI], 11.07-12.97 million). The psychotropic medications most frequently prescribed for elderly patients by office-based physicians were antidepressants and antianxiety agents. The occurrence of visits at which psychotropic medications were prescribed was greater in patients who were over 84 years of age, female, white, or from the western United States. Primary care physicians prescribed the majority of these psychotropic drugs, and most visits to psychiatrists by elderly patients resulted in the prescribing of psychotropic drugs. Office-based physicians prescribed at least one potentially inappropriate psychotropic medication in 2.03 million visits by the elderly (95% CI, 1.70-2.36 million), or 16.87% of visits by the elderly involving prescriptions for psychotropic drugs. The most frequently prescribed potentially inappropriate psychotropic drugs were amitriptyline and long-acting benzodiazepines such as diazepam, chlordiazepoxide, and flurazepam. Logistic regression analyses revealed that inappropriate prescribing of psychotropic drugs for elderly patients was associated with particular patient characteristics (visit due to an injury), drug characteristics (number of medications prescribed and the drug being an antidepressant or antianxiety agent), and physician characteristics (psychiatric specialty and location in the South or Northeast). The patterns of psychotropic prescribing found in the ambulatory setting raise concerns about the quality of care being received by elderly patients with psychiatric illnesses.

摘要

本研究采用了1995年美国国家门诊医疗调查(NAMCS)的数据,以(1)确定美国门诊医生为老年患者开具精神药物的比例;(2)估计该患者群体中开具潜在不适当精神药物的比例;以及(3)确定预测此类处方的任何因素。为了本研究的目的,采用了先前制定的共识标准,将不适当的精神药物定义为老年人应避免使用的药物。根据NAMCS数据,估计老年患者有1202万次就诊开具了精神药物(95%置信区间[CI],1107 - 1297万次)。门诊医生为老年患者最常开具的精神药物是抗抑郁药和抗焦虑药。84岁以上、女性、白人或来自美国西部的患者开具精神药物的就诊次数更多。初级保健医生开具了这些精神药物中的大部分,老年患者看精神科医生的大多数就诊都开具了精神药物。门诊医生在老年患者的203万次就诊中开具了至少一种潜在不适当的精神药物(95% CI,170 - 236万次),占老年患者涉及精神药物处方就诊次数的16.87%。最常开具的潜在不适当精神药物是阿米替林和长效苯二氮䓬类药物,如地西泮、氯氮䓬和氟西泮。逻辑回归分析显示,为老年患者不适当开具精神药物与特定的患者特征(因受伤就诊)、药物特征(开具药物的数量以及药物为抗抑郁药或抗焦虑药)和医生特征(精神科专业以及在南部或东北部的地理位置)有关。门诊环境中精神药物处方的模式引发了对患有精神疾病的老年患者所接受护理质量的担忧。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验