Charlesworth B
Institute for Cell, Animal and Population Biology, Ashworth Laboratories, University of Edinburgh, UK.
Curr Biol. 1998 Jul 2;8(14):R502-4. doi: 10.1016/s0960-9822(98)70318-5.
Although wild-type alleles are generally dominant over mutant alleles, recently established alleles for pesticide resistance are rarely recessive in combination with their progenitors. This seems to be caused by a combination of a 'selective sieve' favouring non-recessive mutations, and the biochemical basis of resistance.
虽然野生型等位基因通常对突变等位基因呈显性,但最近确定的抗农药等位基因与其祖先组合时很少呈隐性。这似乎是由有利于非隐性突变的“选择筛”和抗性的生化基础共同造成的。