Smith G C, Clarke D M, Handrinos D, Dunsis A
Monash University, Department of Psychological Medicine, Melbourne, Australia.
Psychosomatics. 1998 May-Jun;39(3):244-52. doi: 10.1016/S0033-3182(98)71341-6.
Prospective data on 1,360 consecutive inpatients referred to the consultation-liaison psychiatry service of 2 metropolitan general teaching hospitals and diagnoses as having a Depressive Illness Spectrum Disorder were collected by using the MICRO-CARES clinical database system. The distribution of DSM-III-R diagnoses was major depression (MD) 49%; dysthymia (DYS) 15%; organic or substance-induced mood disorder or depressive disorder not otherwise specified (ORG/NOS) 14%; and adjustment disorder with depressed mood (AD) 29%s. Antidepressants were prescribed in 59% of the MD cases, 40% of the DYS cases, 36% of the ORG/NOS cases, and 17% of the AD cases. In confirmed MD, antidepressants were prescribed in 69%, and significantly more often in those who were older, female, had a prior history of physical illness, had a neoplasm or a disorder of the nervous or musculoskeletal systems, had higher Axis IV scores, or were referred because of pain or terminal illness. The patients with confirmed MD prescribed antidepressants had a longer length of stay and were referred later than those not prescribed antidepressants. The results illustrate the importance of all the forms of depression in consultation-liaison psychiatry and the vigor with which all forms are treated.
通过使用MICRO - CARES临床数据库系统,收集了转至两家大都市综合教学医院会诊联络精神科、被诊断患有抑郁疾病谱障碍的1360例连续住院患者的前瞻性数据。《精神疾病诊断与统计手册》第三版修订版(DSM - III - R)诊断分布情况为:重度抑郁症(MD)占49%;心境恶劣障碍(DYS)占15%;器质性或物质所致心境障碍或未另行规定的抑郁障碍(ORG/NOS)占14%;伴抑郁心境的适应障碍(AD)占29%。在MD病例中,59%的患者开具了抗抑郁药;DYS病例中为40%;ORG/NOS病例中为36%;AD病例中为17%。在确诊的MD患者中,69%的患者开具了抗抑郁药,而且在年龄较大、女性、有躯体疾病史、患有肿瘤或神经或肌肉骨骼系统疾病、轴IV评分较高,或因疼痛或绝症而转诊的患者中,开具抗抑郁药的比例明显更高。确诊MD且开具了抗抑郁药的患者住院时间更长,且比未开具抗抑郁药的患者转诊时间更晚。结果说明了所有形式的抑郁症在会诊联络精神病学中的重要性以及对所有形式抑郁症进行积极治疗的情况。