以无明显胃肠道症状的后葡萄膜炎为表现的惠普尔病。
Whipple disease presenting as posterior uveitis without prominent gastrointestinal symptoms.
作者信息
Nishimura J K, Cook B E, Pach J M
机构信息
Department of Ophthalmology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
出版信息
Am J Ophthalmol. 1998 Jul;126(1):130-2. doi: 10.1016/s0002-9394(98)00084-1.
PURPOSE
To describe the clinical presentation and course of Whipple disease in an adult.
METHODS
A 34-year-old man with phthisis bulbi in the right eye secondary to uveitis-induced neovascular glaucoma presented with severe acute posterior uveitis in the left eye. He underwent esophagogastroduodenoscopy and jejunal biopsy for evaluation of anemia. The posterior uveitis was treated with a subtenon injection of triamcinolone.
RESULT
The diagnosis of Whipple disease was confirmed by polymerase chain reaction analysis of the jejunal biopsy that demonstrated Tropheryma whippelii rDNA.
CONCLUSION
Although Whipple disease is typically evident with malabsorption, it can also present as uveitis without prominent gastrointestinal symptoms.
目的
描述一名成人惠普尔病的临床表现及病程。
方法
一名34岁男性，右眼因葡萄膜炎诱发新生血管性青光眼导致眼球痨，左眼出现严重急性后葡萄膜炎。他接受了食管胃十二指肠镜检查和空肠活检以评估贫血情况。后葡萄膜炎采用球后注射曲安奈德进行治疗。
结果
通过对空肠活检组织进行聚合酶链反应分析，证实存在惠普尔嗜组织菌rDNA，从而确诊为惠普尔病。
结论
尽管惠普尔病通常以吸收不良为明显表现，但也可表现为葡萄膜炎且无明显胃肠道症状。
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