Kumar S, Berl T
Department of Medicine, University of Colorado School of Medicine, Denver 80262, USA.
Lancet. 1998 Jul 18;352(9123):220-8. doi: 10.1016/S0140-6736(97)12169-9.
Disorders of serum sodium are both the most common and probably most the poorly understood electrolyte disorders in clinical medicine. In the past few years increased knowledge about the non-osmotic release of vasopressin and the cloning of vasopressin receptors and of vasopressin-regulated water channels (AQP2) has enhanced our understanding of these disorders. Also controversies surrounding the treatment of hyponatraemic patients have led to well-accepted therapeutic guidelines.
血清钠紊乱是临床医学中最常见且可能是理解最不足的电解质紊乱。在过去几年里，关于抗利尿激素的非渗透性释放、抗利尿激素受体以及抗利尿激素调节的水通道（AQP2）克隆的知识不断增加，这增进了我们对这些紊乱的理解。此外，围绕低钠血症患者治疗的争议也催生了广泛认可的治疗指南。
