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婴儿化脓性脑膜炎的前瞻性神经超声研究。

Prospective neurosonographic study in infantile purulent meningitis.

作者信息

Shen E Y, Tsai C Y, Wong T T

机构信息

Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan, R.O.C.

出版信息

Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1998 May-Jun;39(3):180-5.

PMID:9684523
Abstract

Fourteen infants or neonates with purulent meningitis underwent prospective brain sonography follow-up for early detection of intracranial complications. Most patients had 12 scans during a 6 month period. The children's ages ranged from 5 days to 11 months. Early surgical intervention is suggested in progressive ventricular dilatation or severe subdural fluid collection. One patient with hydrocephalus had ventriculoperitoneal shunting. Three patients developed subdural empyema. One had subdural external drainage; and repeat subdural tappings were done in the other two. All these patients recovered without obvious neurologic sequelae. Two other patients developed ventricular dilatation one month after the onset of meningitis. Hydrocephalus ex vacuo was suspected and there were no indications for shunt surgery. These latter two cases had developed mild psychomotor retardation on their last follow-up. This primitive observation suggests that early detection with prospective, sequential sonography follow-up and appropriate surgical intervention for hydrocephalus or subdural fluid collection may lessen the neurologic sequelae in infantile and neonatal purulent meningitis.

摘要

14例患有化脓性脑膜炎的婴儿或新生儿接受了前瞻性脑部超声检查随访,以早期发现颅内并发症。大多数患者在6个月内进行了12次扫描。患儿年龄从5天至11个月不等。对于进行性脑室扩张或严重硬膜下积液,建议早期进行手术干预。1例脑积水患者接受了脑室腹腔分流术。3例患者发生了硬膜下积脓。1例进行了硬膜下外引流;另外2例进行了反复硬膜下穿刺。所有这些患者均康复,无明显神经后遗症。另外2例患者在脑膜炎发病1个月后出现脑室扩张。怀疑为脑外积水,且无分流手术指征。这后2例患者在最后一次随访时出现了轻度精神运动发育迟缓。这一初步观察结果表明,通过前瞻性、序贯性超声检查随访进行早期检测,并对脑积水或硬膜下积液进行适当的手术干预,可能会减少婴儿和新生儿化脓性脑膜炎的神经后遗症。

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