[人酪氨酸转氨酶基因5′端区域介导其糖皮质激素诱导表达的假定元件的定位]
[Localization of putative elements of 5'-region of human tyrosine aminotransferase gene mediating its expression by glucocorticoids].
作者信息
Morozov I V, Smagulova F O, Mertvetsov N P
机构信息
Novosibirsk Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, Russia.
出版信息
Bioorg Khim. 1998 Jun;24(6):433-6.
PMID:9702354
Abstract
The sequence of the region from -1990 to -580 bp of the human tyrosine aminotransferase gene was determined. Computer analysis revealed putative binding sites for the glucocorticoid-receptor complex which mediates regulation of expression of the gene.
摘要
测定了人类酪氨酸转氨酶基因从-1990至-580碱基对区域的序列。计算机分析揭示了糖皮质激素受体复合物的假定结合位点，该复合物介导该基因表达的调控。
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