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[使用VISX 20/20准分子激光矫正近视散光。治疗结果概述]

[Correction of myopic astigmatism with the VISX 20/20 excimer laser. An overview of treatment outcome].

作者信息

Müller H M, Steinkamp G W, Richter R, Koch M J, Roschen A, Ohrloff C

机构信息

Universitäts-Augenklinik Frankfurt Main.

出版信息

Ophthalmologe. 1998 Jun;95(6):413-9. doi: 10.1007/s003470050290.

Abstract

UNLABELLED

The advent of the excimer laser has brought about the potential for improved vision in many individuals with myopia and astigmatism. However, photoastigmatic refractive keratectomy (PARK) remains a matter of controversy. The purpose of our study was to determine the predictability of VISX 20/20 excimer laser photorefractive keratectomy in the treatment of myopic astigmatism.

PATIENTS AND METHODS

Our study comprised 31 eyes of 22 patients with myopic astigmatism. All patients underwent treatment with a VISX 20/20 excimer laser and were followed up for 6 months. Complete 12-month follow-up data were available from 18 eyes. Park was performed in eyes with myopia between -1.5 and -10.0 D and with astigmatism between -0.5 and -5.5 D. Thus, the corresponding spherical equivalent ranged from -1.75 to -10.5 D.

RESULTS

Six months postoperatively, 21/31 (62%) eyes were within +/- 1.0 D of the target refraction and 13/31 (42%) within +/- 0.5 D of the target refraction. In 13 of 15 eyes (87%) with myopia less than -6.0 D, an uncorrected visual acuity of at least 0.8 was noted. In eyes with myopia greater than -6.0 D, 9/16 (56%) showed an uncorrected visual acuity of at least 0.5. Six months after PARK, an increase of one line on the Snellen Visual Acuity Chart was observed in 8/31 (26%) and an increase of two lines was noted in eyes 3/31 (10%). One of 31 eyes (3%) showed an increase of three lines. A decrease in visual acuity of 1 line on the Snellen Visual Acuity Chart was found in 4/31 (13%), and in 3/31 eyes (10%) a decrease of 2-4 lines was noted. Overall, we observed a statistically significant reduction of astigmatism from 1.93 +/- 1.43 D to 0.93 +/- 0.63 D. Reduction of corneal astigmatism less than -1.25 D was not statistically significant. In eyes with astigmatism ranging from -1.25 to -2.5 D or greater than -2.75 D, a significant reduction of the mean astigmatism was noted. The postoperative regression of astigmatic correction was low. However, an axis shift of more than 15 degrees was found in 42%/35% of eyes by subjective refraction (miosis/cycloplegia) and in 33% in corneal topography. No central islands were noted.

CONCLUSION

Photoastigmatic refractive keratectomy (PARK) constitutes a potential means of correcting myopic astigmatism. In eyes with astigmatism greater than -1.0 D a significant reduction of 60% of the mean astigmatism was noted. However, the considerable proportion of eyes with a postoperative axis shift greater than 15 degrees and a decrease in visual acuity of two or more lines indicates that further research is needed on excimer laser surgery to improve the reliability and safety.

摘要

未标注

准分子激光的出现为许多近视和散光患者带来了视力改善的可能性。然而,光性散光性屈光性角膜切削术(PARK)仍存在争议。我们研究的目的是确定VISX 20/20准分子激光屈光性角膜切削术治疗近视散光的可预测性。

患者和方法

我们的研究包括22例近视散光患者的31只眼。所有患者均接受VISX 20/20准分子激光治疗,并随访6个月。18只眼有完整的12个月随访数据。对近视度数在-1.5至-10.0 D之间且散光度数在-0.5至-5.5 D之间的眼睛进行PARK手术。因此,相应的等效球镜度数范围为-1.75至-10.5 D。

结果

术后6个月,21/31(62%)的眼睛屈光度数在目标屈光度数的±1.0 D范围内,13/31(42%)在目标屈光度数的±0.5 D范围内。在近视度数小于-6.0 D的15只眼中,有13只(87%)的裸眼视力至少为0.8。在近视度数大于-6.0 D的眼中,9/16(56%)的裸眼视力至少为0.5。PARK术后6个月,31只眼中有8只(26%)的Snellen视力表视力提高了一行,3只(10%)提高了两行。31只眼中有1只(3%)提高了三行。在31只眼中,有4只(13%)的Snellen视力表视力下降了一行,3只(10%)下降了2至4行。总体而言,我们观察到散光从1.93±1.43 D显著降低至0.93±0.63 D。角膜散光降低小于-1.25 D无统计学意义。在散光度数在-1.25至-2.5 D或大于-2.75 D的眼中,平均散光度数有显著降低。散光矫正术后的回退率较低。然而,主观验光(缩瞳/睫状肌麻痹)发现42%/35%的眼睛散光轴偏移超过15度,角膜地形图检查发现33%的眼睛有此情况。未发现中央岛。

结论

光性散光性屈光性角膜切削术(PARK)是矫正近视散光的一种潜在方法。在散光度数大于-1.0 D的眼中,平均散光度数显著降低了60%。然而,相当比例的眼睛术后散光轴偏移大于15度且视力下降两行或更多行,这表明需要对准分子激光手术进行进一步研究以提高其可靠性和安全性。

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