Beppu T, Ogawa M, Matsuda T, Ohara C, Hirota M, Shimada S, Yamaguchi Y, Yamanaka T
Dept. of Surgery II, Kumamoto University Medical School.
Gan To Kagaku Ryoho. 1998 Jul;25(9):1358-61.
We evaluated the efficacy of microwave coagulation therapy (MCT) in 84 patients with hepatocellular carcinomas (HCC) and 40 with metastatic liver tumors (MLT). The response rates calculated with diagnostic imaging were 92% in HCC and 80% in MLT. The regional recurrence rates were relatively higher in patients with MLT (33%) than in HCC (14%). The average surgical margin in operative MCT group was 11 mm. The cumulative survival rates at three and five years were 63% and 38% in HCC and 43% and 33% in MLT, respectively. The complications were similarly encountered in HCC and MLT (12% versus 13%). When these observations are taken together, MCT is a radical and safe locoregional therapy which can keep an adequate surgical margin and assure long survival.
我们评估了微波凝固疗法（MCT）对84例肝细胞癌（HCC）患者和40例肝转移瘤（MLT）患者的疗效。通过诊断成像计算的缓解率在HCC患者中为92%，在MLT患者中为80%。MLT患者的局部复发率（33%）相对高于HCC患者（14%）。手术MCT组的平均手术切缘为11毫米。HCC患者三年和五年的累积生存率分别为63%和38%，MLT患者分别为43%和33%。HCC和MLT患者出现并发症的情况相似（分别为12%和13%）。综合这些观察结果，MCT是一种根治性且安全的局部区域治疗方法，它能够保持足够的手术切缘并确保长期生存。
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