3',5'-二-O-苯甲酰基取代基对脱氧腺苷/多核苷酸复合物的稳定作用。
Stabilization of deoxyadenosine/polynucleotide complexes by 3',5'-di-O-benzoyl substituents.
作者信息
Chaturvedi S K, Letsinger R L
机构信息
Department of Chemistry, Northwestern University, Evanston, IL 60208, USA.
出版信息
Nucleosides Nucleotides. 1998 Jan-Mar;17(1-3):585-92. doi: 10.1080/07328319808005201.
PMID:9708364
Abstract
3',5'-Di-O-benzoyldeoxyadenosine forms stable dT:dA:dT type complexes with poly(dT) and an oligo(dT)-cholesteryl conjugate in dilute aqueous solution. The benzoyl groups play an essential role in stabilizing these "triple stranded" complexes.
摘要
3',5'-二-O-苯甲酰基脱氧腺苷在稀水溶液中与聚（dT）和寡聚（dT）-胆固醇共轭物形成稳定的dT:dA:dT型复合物。苯甲酰基在稳定这些“三链”复合物中起重要作用。
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