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[北亚三组原住民线粒体DNA的变异性]

[Variability of mitochondrial DNA in three groups of indigenous inhabitants of Northern Asia].

作者信息

Derenko M V, Shields G F

机构信息

Institute of Biological Problems of the North (IBPN), Magadan, Russia,

出版信息

Genetika. 1998 May;34(5):676-81.

PMID:9719916
Abstract

Sequence variants of the hypervariable region I of human mitochondrial DNA (mtDNA) of 125 individuals from three aboriginal population groups of northern Asia (Yakuts, Evens, and Koryaks) were analyzed. Unique types of mtDNA (mitotypes) were discovered in 80% of Koryaks, 78% of Evens, and 59% of Yakuts. The mitotypes observed were clustered into nine phylogenetically related groups, two of which, according to the data on the comparative analysis of Siberian and east Asian populations, were Koryak-specific, and one was Even-specific. Koryaks and Evens exhibited mtDNAs that were highly frequent in Ainu. The results are discussed in terms of genetic differentiation and the ethnogenesis of ethnic groups of northern Asia.

摘要

对来自北亚三个原住民群体(雅库特人、鄂温克人、科里亚克人)的125名个体的人类线粒体DNA(mtDNA)高变区I的序列变异进行了分析。在80%的科里亚克人、78%的鄂温克人以及59%的雅库特人中发现了独特类型的mtDNA(单倍型)。观察到的单倍型被聚类为9个系统发育相关的组,根据对西伯利亚和东亚人群的比较分析数据,其中两组是科里亚克人特有的,一组是鄂温克人特有的。科里亚克人和鄂温克人表现出在阿伊努人中高度常见的mtDNA。从遗传分化和北亚族群的民族起源角度对结果进行了讨论。

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