He J C, Marcos S, Webb R H, Burns S A
Schepens Eye Research Institute, Boston, Massachusetts 02114, USA.
J Opt Soc Am A Opt Image Sci Vis. 1998 Sep;15(9):2449-56. doi: 10.1364/josaa.15.002449.
We used a fast psychophysical procedure to determine the wave-front aberrations of the human eye in vivo. We measured the angular deviation of light rays entering the eye at different pupillary locations by aligning an image of a point source entering the pupil at different locations to the image of a fixation cross entering the pupil at a fixed location. We fitted the data to a Zernike series to reconstruct the wave-front aberrations of the pupil. With this technique the repeatability of the measurement of the individual coefficients was 0.019 micron. The standard deviation of the overall wave-height estimation across the pupil is less than 0.3 micron. Since this technique does not require the administration of pharmacological agents to dilate the pupil, we were able to measure the changes in the aberrations of the eye during accommodation. We found that administration of even a mild dilating agent causes a change in the aberration structure of the eye.
我们采用一种快速心理物理学程序来测定人眼活体的波前像差。我们通过将点光源在不同位置进入瞳孔的图像与固定位置进入瞳孔的注视十字的图像对齐，测量了光线在不同瞳孔位置进入眼睛时的角度偏差。我们将数据拟合到泽尼克级数，以重建瞳孔的波前像差。用这种技术，各个系数测量的重复性为0.019微米。整个瞳孔上波高估计的标准差小于0.3微米。由于该技术不需要使用药理剂来散瞳，我们能够测量调节过程中眼睛像差的变化。我们发现，即使使用温和的散瞳剂也会导致眼睛像差结构的改变。
