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肝切除术后迟发性并发症支气管胆瘘的处理

Management of bronchobiliary fistula as a late complication of hepatic resection.

作者信息

Rose D M, Rose A T, Chapman W C, Wright J K, Lopez R R, Pinson C W

机构信息

Division of Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, Tennessee 37232-4753, USA.

出版信息

Am Surg. 1998 Sep;64(9):873-6.

PMID:9731817
Abstract

Bronchobiliary fistula is an uncommon but remarkable complication after hepatic resection. The case reported illustrates the clinical presentation and preferred initial management of these fistulae. A 61-year-old white male underwent two wedge resections for colorectal metastases to the liver with removal of a portion of the right diaphragm. Four years later, he developed obstructive jaundice secondary to tumor recurrence in the porta hepatis, which required endoscopic stent placement, radiation, and chemotherapy. Almost 2 years later, he developed frank biliptysis. Percutaneous transhepatic cholangiography (PTC) revealed occlusion of the common hepatic duct stent and a bronchobiliary fistula. With adequate reestablishment of common duct drainage, the patient rapidly improved and was discharged free of symptoms. Bronchobiliary fistulae are rare complications of hepatic resection that can present from days to years after operation. Endoscopic retrograde cholangiopancreatography and PTC are the diagnostic studies of choice and offer the possibility of therapeutic intervention. Although large series in the literature emphasize the surgical management of bronchobiliary fistulae, the reoperative procedures tend to be complicated, with a significant morbidity and mortality. Nonsurgical interventions via endoscopic retrograde cholangiopancreatography or PTC are more recently notably successful when resolution of a distal biliary obstruction is accomplished. Only after aggressive attempts at nonoperative, interventional techniques have failed should operative approaches be entertained.

摘要

支气管胆管瘘是肝切除术后一种罕见但值得注意的并发症。本文报道的病例说明了这些瘘管的临床表现及首选的初始治疗方法。一名61岁的白人男性因结直肠癌肝转移接受了两次楔形切除术,并切除了部分右侧膈肌。四年后,他因肝门部肿瘤复发出现梗阻性黄疸,需要进行内镜支架置入、放疗和化疗。近2年后,他出现了明显的胆汁咳出。经皮肝穿刺胆管造影(PTC)显示肝总管支架闭塞及支气管胆管瘘。通过充分重建胆管引流,患者迅速好转并无症状出院。支气管胆管瘘是肝切除术后罕见的并发症,可在术后数天至数年出现。内镜逆行胰胆管造影和PTC是首选的诊断方法,并提供了治疗干预的可能性。尽管文献中的大量病例系列强调支气管胆管瘘的手术治疗,但再次手术往往很复杂,有显著的发病率和死亡率。当远端胆管梗阻得到解决时,通过内镜逆行胰胆管造影或PTC进行的非手术干预最近取得了显著成功。只有在积极尝试非手术介入技术失败后,才应考虑手术方法。

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