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[犬血小板减少症中共振血栓图的敏感性]

[Sensitivity of resonance thrombograms in thrombocytopenia of dogs].

作者信息

Mischke R, Adamik A

机构信息

Klinik für kleine Haustiere, Tierärztlichen Hochschule Hannover.

出版信息

Berl Munch Tierarztl Wochenschr. 1998 Jul-Aug;111(7-8):302-5.

PMID:9741188
Abstract

Based on results of 84 blood samples, taken from 28 dogs suffering from thrombocytopenia, the resonance thrombography turned out as a method with low sensitivity (S) to detect thrombocytopenia in dogs. It was insignificant which one of the two tested resonance thrombographs was taken for measurement and which parameter of the resonance thrombogram (RTG) was used for the thrombocytic potential of haemostasis, the amplitude (RTG-P) or descending time of the platelet side. Only samples containing < or = 25,000 platelets/microliter were reliably measured (S > or = 0.90), whereas thrombocytopenias with > 50,000 platelets/microliter usually resulted in false negative results. The correlation between the platelet count and RTG-P could be almost expressed by a geometrical regression (rs = -0.709). The low sensitivity of RTG mirrors the multifactorial influences and contrasts to the exclusive use of RTG in the screening of thrombocytopenia.

摘要

基于从28只患有血小板减少症的犬采集的84份血样的结果,共振血栓图显示为一种检测犬血小板减少症敏感性较低(S)的方法。使用两种测试的共振血栓图中的哪一种进行测量以及使用共振血栓图(RTG)的哪个参数来评估止血的血小板潜力,即振幅(RTG-P)或血小板侧的下降时间,并无显著差异。只有血小板含量≤25,000/微升的样本能够可靠测量(S≥0.90),而血小板计数>50,000/微升的血小板减少症通常会导致假阴性结果。血小板计数与RTG-P之间的相关性几乎可以用几何回归表示(rs = -0.709)。RTG的低敏感性反映了多因素影响,这与在血小板减少症筛查中单独使用RTG形成对比。

相似文献

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[Sensitivity of resonance thrombograms in thrombocytopenia of dogs].
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