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[翼状胬肉自体结膜-角膜缘移植的长期结果]

[Long-term results of autologous conjunctiva-limbus transplantation in pterygium].

作者信息

Pulte P, Heiligenhaus A, Koch J, Steuhl K P, Waubke T

机构信息

Universität Essen, Augenklinik.

出版信息

Klin Monbl Augenheilkd. 1998 Jul;213(1):9-14. doi: 10.1055/s-2008-1034937.

DOI:10.1055/s-2008-1034937
PMID:9743933
Abstract

BACKGROUND

Conjunctiva-limbus autografting is known as a safe surgical technique for the removal of pterygia, with a low rate of recurrence. However, the long-term effect of this surgical maneuver is not clear. This study now investigates the long-term efficacy of conjunctiva-limbus autografts to prevent pterygium recurrence.

METHODS

Conjunctiva-limbus transplants for primary (n = 62) or recurrent (n = 8) pterygia were reevaluated 11 to 83 months after surgery (mean: 44.97 months). Slit-lamp appearance and photomicrographs were studied with respect to the configuration of the transplant and the recurrence of the fibrovascular tissue typical of pterygia.

RESULTS

Corneal pterygium recurrence has been observed in 2 cases. Fibrovascular tissue was found at the peripheral transplant-margin in 15 cases, and transplant compression towards the limbal margins were detected in further 7 patients. These conjunctival changes have not been observed during the first postoperative months.

CONCLUSIONS

Conjunctiva-limbus autografts in pterygia have excellent efficacy against recurrence within the first few years. The transplant compression and fibrovascular changes within the peripheral conjuctiva seen in this study suggest that recurrencies might, however, develop on the long-term.

摘要

背景

结膜-角膜缘自体移植术是一种已知的用于切除翼状胬肉的安全手术技术,复发率较低。然而,这种手术操作的长期效果尚不清楚。本研究现调查结膜-角膜缘自体移植术预防翼状胬肉复发的长期疗效。

方法

对原发性(n = 62)或复发性(n = 8)翼状胬肉的结膜-角膜缘移植术后11至83个月(平均:44.97个月)进行重新评估。通过裂隙灯外观和显微照片研究移植片的形态以及翼状胬肉典型的纤维血管组织复发情况。

结果

观察到2例角膜翼状胬肉复发。15例在周边移植片边缘发现纤维血管组织,另有7例检测到移植片向角膜缘边缘的压迫。这些结膜变化在术后最初几个月未观察到。

结论

翼状胬肉的结膜-角膜缘自体移植术在最初几年对预防复发具有优异疗效。然而,本研究中观察到的周边结膜内的移植片压迫和纤维血管变化表明,从长期来看可能会出现复发。

相似文献

1
[Long-term results of autologous conjunctiva-limbus transplantation in pterygium].[翼状胬肉自体结膜-角膜缘移植的长期结果]
Klin Monbl Augenheilkd. 1998 Jul;213(1):9-14. doi: 10.1055/s-2008-1034937.
2
Conjunctival-limbal autografts for primary and recurrent pterygia: technique and results.用于原发性和复发性翼状胬肉的结膜-角膜缘自体移植术:技术与结果
Indian J Ophthalmol. 1998 Dec;46(4):203-9.
3
[The pterygium, Autologous conjunctiva-limbus transplantation as treatment].[翼状胬肉,自体结膜-角膜缘移植术作为治疗方法]
Ophthalmologe. 1992 Apr;89(2):143-6.
4
[Autologous conjunctiva-limbus transplantation in treatment of primary and recurrent pterygium].自体结膜-角膜缘移植治疗原发性及复发性翼状胬肉
Ophthalmologe. 1996 Jun;93(3):219-23.
5
[Limbal-conjunctival autograft in pterygium surgery].[翼状胬肉手术中的角膜缘结膜自体移植术]
J Fr Ophtalmol. 2010 Feb;33(2):92-8. doi: 10.1016/j.jfo.2009.12.001. Epub 2010 Feb 4.
6
A comparative study of recurrent pterygium surgery: limbal conjunctival autograft transplantation versus mitomycin C with conjunctival flap.复发性翼状胬肉手术的比较研究:角膜缘结膜自体移植术与丝裂霉素C联合结膜瓣手术的对比
Ophthalmology. 1999 Apr;106(4):817-21. doi: 10.1016/S0161-6420(99)90172-0.
7
Inferior limbal-conjunctival autograft transplantation for recurrent pterygium.自体下睑缘-结膜移植治疗复发性翼状胬肉
Indian J Ophthalmol. 2000 Mar;48(1):21-4.
8
Randomized trial of pterygium surgery with mitomycin C application using conjunctival autograft versus conjunctival-limbal autograft.随机对照试验研究丝裂霉素 C 应用于翼状胬肉手术中,采用结膜自体移植与结膜-角膜缘自体移植的比较。
Ophthalmology. 2012 Feb;119(2):227-32. doi: 10.1016/j.ophtha.2011.08.002. Epub 2011 Dec 6.
9
[Prospective study of surgical therapy of pterygium: bare sclera technique vs. free conjunctiva-limbus transplant].翼状胬肉手术治疗的前瞻性研究:单纯巩膜术式与游离结膜-角膜缘移植术式对比
Ophthalmologe. 1996 Jun;93(3):224-6.
10
Long-term results of bare sclera, limbal-conjunctival autograft and amniotic membrane graft techniques in primary pterygium excisions.原发性翼状胬肉切除术中单纯巩膜、自体角膜缘结膜移植和羊膜移植技术的长期效果
Ophthalmologica. 2009;223(4):269-73. doi: 10.1159/000210444. Epub 2009 Apr 2.

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Korean J Ophthalmol. 2008 Sep;22(3):147-54. doi: 10.3341/kjo.2008.22.3.147.