受体系统合胞体结构对混沌势波动诱导的随机共振的影响。
Effect of syncytium structure of receptor systems on stochastic resonance induced by chaotic potential fluctuation.
作者信息
Kashimori Y, Funakubo H, Kambara T
机构信息
Department of Applied Physics and Chemistry, The University of Electro-Communications, Chofu, Tokyo 182-8585, Japan.
出版信息
Biophys J. 1998 Oct;75(4):1700-11. doi: 10.1016/S0006-3495(98)77612-X.
To study a role of syncytium structure of sensory receptor systems in the detection of weak signals through stochastic resonance, we present a model of a receptor system with syncytium structure in which receptor cells are interconnected by gap junctions. The apical membrane of each cell includes two kinds of ion channels whose gating processes are described by the deterministic model. The membrane potential of each cell fluctuates chaotically or periodically, depending on the dynamical state of collective channel gating. The chaotic fluctuation of membrane potential acts as internal noise for the stochastic resonance. The detection ability of the system increases as the electric conductance between adjacent cells generated by the gap junction increases. This effect of gap junctions arises mainly from the fact that the synchronization of chaotic fluctuation of membrane potential between the receptor cells is strengthened as the density of gap junctions is increased.
为了研究感觉受体系统的合胞体结构在通过随机共振检测微弱信号中的作用，我们提出了一个具有合胞体结构的受体系统模型，其中受体细胞通过缝隙连接相互连接。每个细胞的顶端膜包含两种离子通道，其门控过程由确定性模型描述。每个细胞的膜电位根据集体通道门控的动态状态而混沌地或周期性地波动。膜电位的混沌波动充当随机共振的内部噪声。随着缝隙连接产生的相邻细胞之间的电导增加，系统的检测能力增强。缝隙连接的这种效应主要源于这样一个事实，即随着缝隙连接密度的增加，受体细胞之间膜电位混沌波动的同步性增强。
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