Hitier R, Heisenberg M, Préat T
Institut Alfred Fessard, CNRS, Gif-sur-Yvette, France.
Neuroreport. 1998 Aug 24;9(12):2717-9. doi: 10.1097/00001756-199808240-00006.
In Drosophila melanogaster, adult or larval rearing conditions influence brain structure. In particular, larval density affects the number of fibers forming the mushroom bodies, a neuropil structure involved in olfactory learning. The mushroom bodies receive chemosensory inputs from the antennal lobes at the level of the calyx. In this study we report that larval density affects calyx volume measured shortly after eclosion from the pupal case. We observe that in the memory mutant amnesiac this form of experience-dependent structural plasticity is missing, whereas it is not affected in the learning mutant rutabaga and in the memory mutant radish. Independent of the plasticity effect, the calyces are on average slightly bigger than wild type in amnesiac and smaller in rutabaga flies.
在黑腹果蝇中，成虫或幼虫的饲养条件会影响大脑结构。特别是，幼虫密度会影响构成蘑菇体的纤维数量，蘑菇体是一种参与嗅觉学习的神经纤维结构。蘑菇体在花萼水平接收来自触角叶的化学感觉输入。在本研究中，我们报告幼虫密度会影响从蛹壳羽化后不久测量的花萼体积。我们观察到，在记忆突变体失忆果蝇中，这种形式的经验依赖性结构可塑性缺失，而在学习突变体芜菁甘蓝果蝇和记忆突变体萝卜果蝇中不受影响。与可塑性效应无关，失忆果蝇的花萼平均比野生型略大，而芜菁甘蓝果蝇的花萼则较小。
