Ollagnier E, Frésard A, Guglielminotti C, Carricajo A, Mosnier J F, Alexandre C, Lucht F
Service de Rhumatologie, Hôpital de Bellevue, CHU de Saint-Etienne.
Presse Med. 1998;27(17):800-3.
Mycobacterium xenopi is a potential pathogen for man and can cause bone and joint infections, particularly spondylodiscitis. Most cases of infection occur in fragilized patients and are found more and more often in AIDS patients.
A 41-year-old HIV+ woman developed cervical spondylodiscitis due to Mycobacterium xenopi infection. The strain was isolated from a discovertebral biopsy and was resistant to several antibiotics. Outcome was unfavorable.
Most of the cases reported to date have involved spondylodiscitis of the thoracic or lumbar spine. To our knowledge, this is the first report of cervical spondylodiscitis dut to Mycobacterium xenopi in an HIV+ patient. Antibiotic combinations using fluoroquinolones and new macrolides are usually prescribed. Such protocols may provide cure of these opportunistic infections in immunodeficient patients.
偶发分枝杆菌是一种潜在的人类病原体，可引起骨与关节感染，尤其是脊椎间盘炎。大多数感染病例发生在身体虚弱的患者中，并且在艾滋病患者中越来越常见。
一名41岁的HIV阳性女性因偶发分枝杆菌感染患上颈椎脊椎间盘炎。该菌株从椎间盘活检中分离出来，对多种抗生素耐药。结果不佳。
迄今为止报告的大多数病例都涉及胸椎或腰椎的脊椎间盘炎。据我们所知，这是第一例关于HIV阳性患者因偶发分枝杆菌引起颈椎脊椎间盘炎的报告。通常会开具使用氟喹诺酮类和新型大环内酯类的抗生素联合用药方案。这样的方案可能治愈免疫缺陷患者的这些机会性感染。
