Lepaux D J, Wahl D, Schuhmacher H, Nace L, Angioi M, Briançon S, Delorme N, Laurain M C, Maurer P, Pinelli C, Lecompte T
Centre hospitalier régional universitaire de Nancy.
Presse Med. 1998 Jan 24;27(3):100-5.
In an effort to improve the prevention of venous thromboembolism, the Nancy University Hospitals conducted a survey of medical practice concerning indications for preventive therapy and surveillance of platelet counts and anti Xa activity.
The survey involved 163 medical files. Questionnaires were filled out in 6 units (3 medical wards and 3 intensive care units).
Indications for preventive therapy were found to be quite variable with the exception of very low risk of thromboembolism where the treat/do not treat ratio was 0.1/1, indicating a clear tendency for abstention. This ratio was 0.77/1 and 0.38/1 respectively for low and moderate risk and 2/1 for high risk. There was undoubtedly a ward effect. The attitudes in practice tended toward non-prevention in patients without limited mobility. For platelet counts, an initial count was performed in 95% of the cases and during treatment in 38% although the specific rates were not the same for different types of units. Anti-Xa activity, which according to prevention recommendations need not to be determined, was not monitored in 88% of the cases. In accordance with prevention recommendations, anti-Xa activity was not determined in 88% of the cases.
Further progress is needed in the prevention of venous thromboembolism and should be based on wider use of existing methods.
为了改进静脉血栓栓塞的预防措施,南锡大学医院开展了一项关于预防性治疗指征以及血小板计数和抗Xa活性监测的医疗实践调查。
该调查涉及163份医疗档案。在6个科室(3个内科病房和3个重症监护病房)填写了调查问卷。
除血栓栓塞风险极低的情况外,预防性治疗的指征差异很大,在血栓栓塞风险极低的情况下,治疗/不治疗的比例为0.1/1,表明明显倾向于不进行治疗。低风险和中度风险的这一比例分别为0.77/1和0.38/1,高风险为2/1。无疑存在科室效应。实际态度倾向于对活动不受限的患者不进行预防。对于血小板计数,95%的病例进行了初始计数,治疗期间进行计数的比例为38%,不过不同类型科室的具体比例不同。根据预防建议无需测定的抗Xa活性,在88%的病例中未进行监测。根据预防建议,88%的病例未测定抗Xa活性。
静脉血栓栓塞的预防需要进一步改进,应基于更广泛地使用现有方法。