Lombardi R, Zampedri L, Rodriguez I, Alegre S, Ursu M, Di Fabio M
Centro de Nefrologia, Universidad de la Republica, Montevideo, Uruguay.
Ren Fail. 1998 Sep;20(5):725-32. doi: 10.3109/08860229809045169.
The goal of the present study was to identify variables associated with the outcome of patients with acute renal failure (ARF) of septic origin, using multivariate analysis. The records of 168 patients were reviewed retrospectively and a crude mortality of 74% was found. Both univariate as well as multivariate analysis demonstrated an association between mortality and variables which depended on patient related factors. These included age over 60 years and several underlying diseases such as pneumonia, peritonitis, and organ dysfunction. Only one variable (late oliguria) related to the ARF itself. Thus, outcome seems related to underlying disease more than to severity of ARF.
本研究的目的是通过多变量分析确定与脓毒症所致急性肾衰竭(ARF)患者预后相关的变量。对168例患者的记录进行了回顾性分析,发现粗死亡率为74%。单变量分析和多变量分析均表明死亡率与取决于患者相关因素的变量之间存在关联。这些因素包括60岁以上的年龄以及几种基础疾病,如肺炎、腹膜炎和器官功能障碍。只有一个变量(晚期少尿)与ARF本身相关。因此,预后似乎与基础疾病的关系更大,而非ARF的严重程度。