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急性结直肠梗阻:支架置入姑息治疗——一项多中心研究结果

Acute colorectal obstruction: stent placement for palliative treatment--results of a multicenter study.

作者信息

de Gregorio M A, Mainar A, Tejero E, Tobío R, Alfonso E, Pinto I, Fernández R, Herrera M, Fernández J A

机构信息

Interventional Radiology Section, Hospital Clínico Universitario, C/San Juan Bosco, Zaragoza, Spain.

出版信息

Radiology. 1998 Oct;209(1):117-20. doi: 10.1148/radiology.209.1.9769821.

Abstract

PURPOSE

To evaluate the usefulness of stent implantation as a palliative treatment in patients with acute colonic obstruction who are not surgical candidates.

MATERIALS AND METHODS

Twenty-four patients (eight women, 16 men; age range, 60-98 years) with acute colonic obstruction underwent colonic stent placement. In nine patients, the procedure was considered a primary palliative treatment; seven patients had a previous diagnosis of disseminated neoplastic disease, and two were not surgical candidates because of their poor general condition. In the remaining 15 patients, stent placement was considered the definitive palliative treatment after tumor staging. The mean time of follow-up was 8.4 months (range, 1-24 months) for patients who lived and 6.3 months (range, 1-12 months) for those who died.

RESULTS

Stent placement was successful in all patients. Clinical and radiographic findings of bowel obstruction resolved within 24 hours after stent placement in 23 (96%) patients. None of the patients required colostomy for bowel decompression after immediate stent placement. Complications developed in 10 (42%) patients: Two (8%) patients had mild rectal bleeding; three (12%), abdominal pain; two (8%), malpositioning of the stent; two (8%), pseudo-obstructive episodes due to fecal impaction; and one (4%), occlusive tumor ingrowth into the stent lumen. One (4%) patient underwent surgery to resolve stent malfunction due to poor positioning. Two (8.3%) patients--one with malpositioning of the prosthesis and the other with stent occlusion--required a new stent. The remaining complications required no further treatment. The mortality rate at 6 months was 24%. Eight patients were alive at the time this article was written.

CONCLUSION

Colorectal stent placement resulted in successful palliation of acute colonic obstruction in patients with disseminated neoplastic disease.

摘要

目的

评估支架植入术作为非手术候选急性结肠梗阻患者姑息治疗方法的有效性。

材料与方法

24例急性结肠梗阻患者(8例女性,16例男性;年龄范围60 - 98岁)接受了结肠支架置入术。9例患者,该手术被视为主要姑息治疗;7例患者先前诊断为播散性肿瘤疾病,2例因全身状况差而不是手术候选者。其余15例患者,支架置入术被视为肿瘤分期后的确定性姑息治疗。存活患者的平均随访时间为8.4个月(范围1 - 24个月),死亡患者为6.3个月(范围1 - 12个月)。

结果

所有患者支架置入均成功。23例(96%)患者在支架置入后24小时内肠梗阻的临床和影像学表现得到缓解。立即置入支架后,无一例患者需要进行结肠造口术以缓解肠腔压力。10例(42%)患者出现并发症:2例(8%)患者有轻度直肠出血;3例(12%),腹痛;2例(8%),支架位置不当;2例(8%),因粪便嵌塞导致假性梗阻发作;1例(4%),肿瘤向内生长阻塞支架管腔。1例(4%)患者因支架位置不佳接受手术以解决支架故障。2例(8.3%)患者——1例假体位置不当,另1例支架闭塞——需要置入新支架。其余并发症无需进一步治疗。6个月时死亡率为24%。撰写本文时,8例患者存活。

结论

结直肠支架置入术成功缓解了播散性肿瘤疾病患者的急性结肠梗阻。

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