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不动杆菌属细菌

[Bacteria of the Acinetobacter genus].

作者信息

Joly-Guillou M L

机构信息

Service de Microbiologie (Dr Boussougant), Hôpital Louis Mourier, Colombes, France.

出版信息

Pathol Biol (Paris). 1998 Apr;46(4):245-52.

PMID:9769904
Abstract

Bacteria of the Acinetobacter genus received little attention for many years because of their weak pathogenic potential and changing taxonomy. Since the introduction starting in the 1980s of an ever increasing number of antimicrobials, these organisms have demonstrated their ability to adapt. They are causing an increasing number of nosocomial infections, most notably in intensive care units. The selection pressure exerted by antimicrobials and the use of increasingly invasive diagnostic and therapeutic procedures are the main factors that promote emergence of Acinetobacter in high-risk patients. Acinetobacter exhibit a high level of resistance to antimicrobials and are capable of persisting in hostile environments (humidity or dryness, presence of some antiseptics). As a result, they can cause nosocomial outbreaks. Identification of carriers and colonized patients, rigorous isolation, and scrupulous cleaning procedures are effective control measures. Despite these efforts, however, Acinetobacter baumannii now contributes a significant proportion of nosocomial infections.

摘要

多年来,不动杆菌属细菌因其致病潜力较弱和分类不断变化而受到的关注较少。自20世纪80年代开始引入越来越多的抗菌药物以来,这些微生物已显示出它们的适应能力。它们导致越来越多的医院感染,最显著的是在重症监护病房。抗菌药物施加的选择压力以及越来越多地使用侵入性诊断和治疗程序是促使不动杆菌在高危患者中出现的主要因素。不动杆菌对抗菌药物表现出高度耐药性,并且能够在恶劣环境(潮湿或干燥、存在一些防腐剂)中存活。因此,它们可导致医院感染暴发。识别携带者和定植患者、严格隔离以及细致的清洁程序是有效的控制措施。然而,尽管做出了这些努力,鲍曼不动杆菌目前在医院感染中仍占很大比例。

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