Zhang X, Tang X, Zhang Z, Du H, Li B
Department of Neurology, Beijing Tongren Hospital, China.
Chin Med J (Engl). 1997 Nov;110(11):856-8.
To recognize different forms of Guillain-Barre syndrome (GBS) in northern China.
Twenty-one cases were found in two counties of Beijing suburb from January 1993, to December, 1994. Multiple electrophysiological studies including magnetic motor evoked potential, F-wave, motor and sensory conduction velocity, blink reflex and needle electromyography were conducted on nineteen cases of them. Twelve cases accepted electrophysiological follow-up study.
Altogether 17 cases showed demyelination features in multiple electrodiagnosis. Ten cases of them were accompanied by different extent of axonal lesion. Only one case showed main or primary axonal lesion.
Demyelination is the main type of pathophysiological lesion of GBS in Beijing suburb. Different extent of axonal lesion can appear in some cases, but primary and main axonal type is rare in this area.
识别中国北方不同类型的吉兰-巴雷综合征(GBS)。
1993年1月至1994年12月间,在北京郊区的两个县发现了21例病例。对其中19例进行了多项电生理研究,包括磁运动诱发电位、F波、运动和感觉传导速度、瞬目反射及针极肌电图检查。12例接受了电生理随访研究。
17例在多项电诊断中表现为脱髓鞘特征。其中10例伴有不同程度的轴索性损害。仅1例表现为主要或原发性轴索性损害。
脱髓鞘是北京郊区GBS病理生理损害的主要类型。部分病例可出现不同程度的轴索性损害,但该地区原发性及主要为轴索型的病例罕见。