Strowig S M, Raskin P
University of Texas Southwestern Medical Center, Department of Internal Medicine, Dallas 75235-8858, USA.
Diabetes Care. 1998 Oct;21(10):1694-8. doi: 10.2337/diacare.21.10.1694.
To determine the effect on glycemic control in intensively treated type 1 diabetic patients using a blood glucose meter with storage capability and computer-assisted analyses.
Glycemic control was assessed in 22 intensively treated adults with type 1 diabetes for 12 months while using a meter without memory, followed by 12 months while using a meter with memory. Log books were used to assist patients in managing aspects of the diabetes treatment plan during the first 12-month period, and computer-assisted analyses were used when the meter with memory was used. GHb levels were measured monthly throughout the 24 months of observation.
The mean GHb level averaged across all patients during the period of memory meter use (6.4%) was significantly lower than that during the period of meter use without memory (6.9%) (P=0.0004). The change in GHb levels from each period-specific baseline level occurred at significantly different slopes (P=0.046) when adjusted for baseline GHb level. In addition, the downward trend in GHb level was greater in those patients who increased the frequency of testing the most (r=-0.54, P=0.01).
Use of a meter with memory in conjunction with computer-generated analyses of stored blood glucose test results can lead to improved glycemic control when used by a group of intensively treated adult diabetic patients. Improvement in glycemic control was related to frequency of blood glucose testing.
使用具有存储功能和计算机辅助分析功能的血糖仪,确定其对强化治疗的1型糖尿病患者血糖控制的影响。
对22名接受强化治疗的成年1型糖尿病患者的血糖控制情况进行了为期12个月的评估,期间使用无记忆功能的血糖仪,随后再使用12个月有记忆功能的血糖仪。在最初的12个月期间,使用日志本协助患者管理糖尿病治疗计划的各个方面,在使用有记忆功能的血糖仪时则采用计算机辅助分析。在整个24个月的观察期内每月测量糖化血红蛋白(GHb)水平。
在使用有记忆功能血糖仪期间,所有患者的平均GHb水平(6.4%)显著低于使用无记忆功能血糖仪期间(6.9%)(P = 0.0004)。在根据基线GHb水平进行调整后,各阶段特定基线水平的GHb水平变化呈现出显著不同的斜率(P = 0.046)。此外,血糖检测频率增加最多的患者,其GHb水平下降趋势更大(r = -0.54,P = 0.01)。
一组接受强化治疗的成年糖尿病患者使用有记忆功能的血糖仪并结合对存储的血糖检测结果进行计算机生成分析,可改善血糖控制。血糖控制的改善与血糖检测频率有关。