Hoque M S, Ali S M, Waiz A
Department of Community Medicine, Armed Forces Medical Institute, Dhaka.
Bangladesh Med Res Counc Bull. 1998 Apr;24(1):14-9.
A controlled clinical trial was conducted to determine whether combined exercise training and diet alone reduce blood pressure (BP), body weight and body mass index (BMI) in three weeks. Twenty eight patients with diastolic BP < or = 110 mmHg were assigned to a hypertensive group and another 28 subjects with diastolic BP < or = 90 mmHg were subjected to the same intervention as control group (normotensive group). Exercise training and diet reduced diastolic BP by 24.7 mmHg and systolic BP by 32.8 mmHg in hypertensive group. There was a mean decreased of 5.3 mmHg in the diastolic BP in the normotensive group (P < 0.001). The systolic BP decreased only minimally. The weight loss ranged from 1 kg to 3 kg in hypertensive and 1 kg to 2 kg in the normotensive group. The mean weight loss was 1.6 kg (0.7) in hypertensive and 1.5 kg (0.5) in the normotensive group. In both the groups the weight reduction was highly significant (P < 0.001) and moderately positive correlation was also noted with the fall of BPs. The mean fall of BMI was 0.61 kg/m2 (0.21) and 0.51 (0.2) kg/m2 in the hypertensive and normotensive groups respectively. The findings indicated that a combined exercise training and dietary program could lower BP in patients with mild to moderate hypertension, but its long-term consequences on morbidity and mortality remain to be determined.
进行了一项对照临床试验,以确定单纯的联合运动训练和饮食干预在三周内是否能降低血压(BP)、体重和体重指数(BMI)。将28例舒张压≤110mmHg的患者分配到高血压组,另外28例舒张压≤90mmHg的受试者作为对照组(血压正常组)接受相同干预。高血压组的运动训练和饮食使舒张压降低了24.7mmHg,收缩压降低了32.8mmHg。血压正常组的舒张压平均下降了5.3mmHg(P<0.001)。收缩压仅略有下降。高血压组体重减轻1至3千克,血压正常组体重减轻1至2千克。高血压组平均体重减轻1.6千克(0.7),血压正常组平均体重减轻1.5千克(0.5)。两组的体重减轻均非常显著(P<0.001),并且与血压下降也存在中度正相关。高血压组和血压正常组的BMI平均下降分别为0.61kg/m²(0.21)和0.51(0.2)kg/m²。研究结果表明,联合运动训练和饮食方案可以降低轻度至中度高血压患者的血压,但其对发病率和死亡率的长期影响仍有待确定。