Mendelsohn F O, Santos R M, Crowley J J, Lederman R J, Cobb F R, Phillips H R, Weissman N J, Stack R S
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Am Heart J. 1998 Oct;136(4 Pt 1):600-5. doi: 10.1016/s0002-8703(98)70005-5.
We report the first series of simultaneously delivered stents used to treat stenosis of the aortic bifurcation. Surgical treatment of aortoiliac occlusive disease carries up to a 3% mortality rate. Percutaneous balloon techniques to treat aortic bifurcation stenosis, although safer, are still associated with up to a 9% incidence of dissection, thrombosis, or significant residual stenosis. Kissing stent insertion should decrease the incidence of these complications.
Twenty patients underwent kissing stent insertion. Suitable candidates included patients with symptoms of lower limb ischemia and significant atherosclerotic lesions in both ostial common iliac arteries (n = 15) or with extremely complex single ostial iliac stenoses (n = 5). Palmaz stents were delivered simultaneously to both limbs of the aortic bifurcation.
Kissing stent insertion was successfully performed in all 20 patients without acute complications. Mean percent stenosis decreased from 46.2%+/-24.8% to -6.8%+/-13.3% (P = .0001) in the right iliac artery, 42.3%+/-22.8% to -1.6% +/-18.1% (P = .0001) in the left iliac artery, and 19.1%+/-16.6% to 2.3%+/-16.4% (P= .0008) in the distal aorta. Intermittent claudication symptoms were improved in 18 (95%) of 19 patients with 12 (63%) of 19 patients becoming totally asymptomatic. The strongest predictor of clinical outcome after kissing stent insertion was the preprocedural extent of femoropopliteal disease: 8 (89%) of 9 patients with femoropopliteal narrowing <75% bilaterally became completely asymptomatic at follow-up compared with only 3 (30%) of 10 patients with more severe stenoses (P = .02).
We have demonstrated in 20 patients that stenoses of the aortic bifurcation can be treated effectively with kissing stents with few serious adverse events.
我们报道了首例用于治疗主动脉分叉处狭窄的同步置入支架系列病例。腹主动脉髂动脉闭塞性疾病的外科治疗死亡率高达3%。经皮球囊技术治疗主动脉分叉狭窄,虽然更安全,但仍有高达9%的夹层、血栓形成或严重残余狭窄发生率。置入吻合支架应能降低这些并发症的发生率。
20例患者接受了吻合支架置入。合适的候选患者包括有下肢缺血症状且双侧髂总动脉开口处有明显动脉粥样硬化病变的患者(n = 15)或有极其复杂的单侧髂动脉开口狭窄的患者(n = 5)。将帕尔马兹支架同步置入主动脉分叉的双分支。
20例患者均成功进行了吻合支架置入,无急性并发症。右髂动脉平均狭窄百分比从46.2%±24.8%降至-6.8%±13.3%(P = .0001),左髂动脉从42.3%±22.8%降至-1.6%±18.1%(P = .0001),远端主动脉从19.1%±16.6%降至2.3%±16.4%(P = .0008)。19例患者中有18例(95%)间歇性跛行症状得到改善,19例患者中有12例(63%)完全无症状。置入吻合支架后临床结果的最强预测因素是术前股腘动脉疾病的程度:双侧股腘动脉狭窄<75%的9例患者中有8例(89%)在随访时完全无症状,而10例狭窄更严重的患者中只有3例(30%)无症状(P = .02)。
我们在20例患者中证明,吻合支架可有效治疗主动脉分叉处狭窄,严重不良事件较少。