Richter K, Hamm B, Heywang-Köbrunner S H, Fobbe F, Prihoda H, Schmitt K J, Frohberg H D, Winzer K J, Aldinger H U, Guski H, Döinghaus K, Löhr G
Institut für Röntgendiagnostik, Charité, Humboldt Universität, Berlin.
Rofo. 1998 Sep;169(3):245-52. doi: 10.1055/s-2007-1015085.
A prospective study on the differentiation of breast lesions was carried out using experimental combination schemes of mammography and automatic sonography.
X-ray mammograms and a B image from automatic sonography of 39 malignant and 41 benign lesions as well as 40 cases without lesions were separately examined by four experienced diagnosticians. The observers differentiated the findings mammographically and by measurement in the B images.
For two examiners the combination of mammography and automatic sonography gave with regard to the differentiation of breast lesions an improvement in sensitivity of 3 or 5% and in specificity of 31 and 18%, respectively, as compared to mammography alone while for the other two examiners an improved specificity of 21 and 36%, respectively, was accompanied by an 8 and 10% decrease in sensitivity as compared to mammography alone.
The differentiating criteria from automatic sonography and mammography can, in principle, be used to evaluate the dignity of breast lesions. However, an optimization is necessary since the improvement in specificity does not compensate the loss in sensitivity.
采用乳腺钼靶摄影与自动超声检查的实验组合方案，对乳腺病变的鉴别诊断进行前瞻性研究。
4名经验丰富的诊断医师分别对39例恶性病变、41例良性病变以及40例无病变病例的乳腺钼靶X线片和自动超声检查的B超图像进行检查。观察者通过乳腺钼靶摄影及B超图像测量来鉴别检查结果。
与单纯乳腺钼靶摄影相比，对于两名检查者而言，乳腺钼靶摄影与自动超声检查相结合在乳腺病变鉴别诊断方面，敏感性分别提高了3%或5%，特异性分别提高了31%和18%；而对于另外两名检查者，特异性分别提高了21%和36%，但与单纯乳腺钼靶摄影相比，敏感性分别降低了8%和10%。
自动超声检查和乳腺钼靶摄影的鉴别标准原则上可用于评估乳腺病变的性质。然而，由于特异性的提高无法弥补敏感性的损失，因此有必要进行优化。
