West J D
J Embryol Exp Morphol. 1976 Aug;36(1):151-61.
Sections of adult chimaeric livers have been histochemically stained for beta-glucuronidase activity and patches of two cell populations visualized. A one-dimensional clonal analysis has been used to estimate the number of coherent clones in the adult liver. The data are consistent with a total of 9-22 million regular, coherent clones, comprising 10-34 nuclei, or a smaller number of irregular, branched coherent clones. Both of these alternatives suggest considerable cell mixing during liver morphogenesis.
已对成年嵌合肝脏的切片进行了β-葡萄糖醛酸酶活性的组织化学染色，并观察到了两个细胞群体的斑块。已使用一维克隆分析来估计成年肝脏中连贯克隆的数量。数据表明，共有900万至2200万个规则、连贯的克隆，包含10至34个细胞核，或者是数量较少的不规则、分支的连贯克隆。这两种情况都表明在肝脏形态发生过程中存在大量细胞混合。
