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用低能量窄光子束锐化高能电子束的半影区。

Sharpening the penumbra of high energy electron beams with low weight narrow photon beams.

作者信息

Korevaar E W, van Vliet R J, Woudstra E, Heijmen B J, Huizenga H

机构信息

Department of Clinical Physics, Daniel den Hoed Cancer Center, University Hospital Rotterdam, The Netherlands.

出版信息

Radiother Oncol. 1998 Aug;48(2):213-20. doi: 10.1016/s0167-8140(98)00030-9.

Abstract

BACKGROUND AND PURPOSE

High energy (20-50 MeV) electron beams, available from the MM50 Racetrack Microtron, can be used for the treatment of deep-seated tumors. A disadvantage is the increasing penumbra width as a function of depth. By the addition of a narrow (typically 1 cm wide) photon beam near the field edge, the 50-90% penumbra width of the electron beam is reduced, yielding a significantly increased effective field size.

MATERIALS AND METHODS

For rectangular electron beams in a water phantom (energies 25 and 40 MeV, field sizes 5 x 5-15 x 15 cm2) a computer program was used to optimize the photon beam parameters (position, weight and width) to obtain a combined beam with the sharpest penumbra at the optimization depth and a beam flatness within certain constraints. The study furthermore included penumbra sharpening of an irregular multileaf collimator-shaped field.

RESULTS AND CONCLUSION

At optimization depths near R90, photon beam addition reduces the penumbra width by 40-50% (from 15-20 mm to 8-10 mm). Beam flatness at the optimization depth is within +/-5% and hot-spots are < or =120% for all depths. By the addition of narrow photon beams around the rectangular or irregular field, the electron field width can be reduced by 1-3 cm, while the effective field size is maintained.

摘要

背景与目的

MM50跑道式电子回旋加速器产生的高能(20 - 50 MeV)电子束可用于治疗深部肿瘤。缺点是半影宽度随深度增加。通过在射野边缘附近添加一束窄的(通常1 cm宽)光子束,电子束的50 - 90%半影宽度减小,有效射野尺寸显著增大。

材料与方法

对于水模中的矩形电子束(能量25和40 MeV,射野尺寸5×5 - 15×15 cm²),使用计算机程序优化光子束参数(位置、权重和宽度),以在优化深度获得半影最清晰且在一定约束内射野平坦度良好的合成束。该研究还包括对不规则多叶准直器形状射野的半影锐化。

结果与结论

在接近R90的优化深度处,添加光子束可使半影宽度减小40 - 50%(从15 - 20 mm减小到8 - 10 mm)。优化深度处的射野平坦度在±5%以内,所有深度的热点均≤120%。通过在矩形或不规则射野周围添加窄光子束,电子射野宽度可减小1 - 3 cm,同时保持有效射野尺寸。

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