Cooper B W, Morganelli E
Division of Infectious Diseases, Hartford Hospital, USA.
Conn Med. 1998 Sep;62(9):515-7.
Invasive disease due to Group B streptococci has been increasingly recognized as a problem in chronically ill adults. We studied all adults presenting with bacteremia due to Group B streptococci at Hartford Hospital over a period of more than five years. Fifty-nine episodes of septicemia occurred with a mortality rate of 15.3%. Markers for mortality included cirrhosis, azotemia, transaminase elevation, respiratory distress on admission, and ionized hypocalcemia Although commonly thought of as a maternal and pediatric pathogen, nonpregnant, chronically ill adults make up the vast majority of patients with Group B streptococcal sepsis.
B族链球菌引起的侵袭性疾病在慢性病成年患者中日益被视为一个问题。我们研究了哈特福德医院五年多来所有因B族链球菌引起菌血症的成年患者。发生了59例败血症,死亡率为15.3%。死亡的标志物包括肝硬化、氮质血症、转氨酶升高、入院时呼吸窘迫和离子钙降低。尽管通常认为B族链球菌是母婴病原体,但非妊娠慢性病成年患者占B族链球菌败血症患者的绝大多数。