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甲状旁腺切除术后的饥饿骨综合征

Hungry bone syndrome following parathyroidectomy.

作者信息

Headley C M

机构信息

Veterans Administration Medical Center, Memphis, TN, USA.

出版信息

ANNA J. 1998 Jun;25(3):283-9; quiz 290-1.

PMID:9801484
Abstract

Hyperparathyroid-associated bone disease is known to affect quality of life and contribute to premature morbidity in the end stage renal disease (ESRD) population. Failure to adequately suppress parathyroid hormone secretion with medical management often warrants parathyroidectomy. Hypocalcemia frequently occurs after parathyroidectomy. A state of marked and prolonged hypocalcemia is termed "hungry bone syndrome." Biochemical and clinical criteria associated with development of hungry bone syndrome assist with identification of those at risk and facilitates postoperative management.

摘要

甲状旁腺功能亢进相关骨病已知会影响生活质量,并导致终末期肾病(ESRD)患者过早发病。药物治疗未能充分抑制甲状旁腺激素分泌时,往往需要进行甲状旁腺切除术。甲状旁腺切除术后常发生低钙血症。显著且持续时间较长的低钙血症状态被称为“骨饥饿综合征”。与骨饥饿综合征发生相关的生化和临床标准有助于识别有风险的患者,并促进术后管理。

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