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[微创手术与克罗恩病]

[Minimally invasive surgery and Crohn disease].

作者信息

Hildebrandt U, Ecker K W, Feifel G

机构信息

Abteilung für Allgemeine Chirurgie, Abdominal- und Gefässchirurgie, Universitätskliniken des Saarlandes, Homburg.

出版信息

Chirurg. 1998 Sep;69(9):915-21. doi: 10.1007/s001040050513.

Abstract

Patients with Crohn's disease are operated on with a morbidity of 15% and a mortality of 0% if the indication for surgery is decided in good time. After ileocecal resection the probability of having a second resection in 15-20 years is about 50%. When elective surgery is done at an early disease stage, ileocecal resections and reoperations for anastomotic stenosis can be performed by assisted laparoscopy assisted. Laparoscopic colonic resections are done more rarely. Acute and life-threatening conditions such as obstruction, perforation and sepsis are excluded from the laparoscopic approach. In a combined series of 222 laparoscopic resections for Crohn's disease, the following types of surgery were included: ileocecal resections (75), anastomotic resections (26), small intestinal resections (4), loop ileostomies (17), gastrojejunostomies (3), partial colonic resections (15), colectomies (16), loop colostomies (2) and one adhesiolysis. Two patients who sustained intraoperative bleeding underwent conversion of laparotomy. The conversion rate ranged from 0 to 22%. Reasons for 32 conversions were: large inflammatory mass (14), severe inflammation (5), fistula (3), abscess (1), perforation (1), small intestine dilation (1) and mesenteric thickening (1). Mean operative time for ileocecal resections ranged from 105 to 200 min. The postoperative hospital stay was 5 to 8 days. As more experience is gained and technical improvement is achieved, additional procedures such as resolution of severe adhesions, fistula closure and resections of colonic segments will be offered to the majority of patients who require elective surgery for localized Crohn's disease.

摘要

如果能及时确定手术指征,克罗恩病患者手术的发病率为15%,死亡率为0%。回盲部切除术后15至20年再次切除的概率约为50%。在疾病早期进行择期手术时,回盲部切除及吻合口狭窄的再次手术可通过辅助腹腔镜完成。腹腔镜结肠切除术较少进行。腹腔镜手术不适用于肠梗阻、穿孔和脓毒症等急性且危及生命的情况。在一组222例克罗恩病腹腔镜切除术的综合病例中,包括以下几种手术类型:回盲部切除术(75例)、吻合口切除术(26例)、小肠切除术(4例)、袢式回肠造口术(17例)、胃空肠吻合术(3例)、部分结肠切除术(15例)、结肠切除术(16例)、袢式结肠造口术(2例)和1例粘连松解术。两名术中出血的患者转为开腹手术。中转率为0%至22%。32例中转的原因包括:巨大炎性包块(14例)、严重炎症(5例)、瘘管(3例)、脓肿(1例)、穿孔(1例)、小肠扩张(1例)和肠系膜增厚(1例)。回盲部切除术的平均手术时间为105至200分钟。术后住院时间为5至8天。随着经验的积累和技术的改进,对于大多数因局限性克罗恩病需要择期手术的患者,将提供更多的手术方式,如严重粘连松解、瘘管闭合和结肠段切除等。

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