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酒精性肝病:美国胃肠病学会的拟议建议

Alcoholic liver disease: proposed recommendations for the American College of Gastroenterology.

作者信息

McCullough A J, O'Connor J F

机构信息

Center of Nutrition and Metabolism, Metro Health Medical Center, Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44109-1998, USA.

出版信息

Am J Gastroenterol. 1998 Nov;93(11):2022-36. doi: 10.1111/j.1572-0241.1998.00587.x.

Abstract

OBJECTIVE

The objective of this work was to develop practice guidelines for the management of alcoholic liver disease.

METHOD

A computerized search using the Medline Data Base from 1966-July 1997 was performed with the search headings; alcohol, alcoholic hepatitis, alcoholic liver disease, liver transplant, diagnosis, epidemiology, human, and English only. All randomized controlled trials, case-control studies, and meta-analyses were read in depth. A manual search was also done using references from each retrieved report, review articles, editorials, postgraduate course syllabi, and textbooks. In the subsequent review, evidence was evaluated using a hierarchical scale with randomized, controlled trials given the most importance. Abstracts presented at national meetings were included only when unique data were obtained from those studies.

摘要

目的

本研究的目的是制定酒精性肝病管理的实践指南。

方法

利用1966年至1997年7月的医学数据库进行计算机检索,检索词为:酒精、酒精性肝炎、酒精性肝病、肝移植、诊断、流行病学、人类,且仅为英文。对所有随机对照试验、病例对照研究和荟萃分析进行了深入阅读。还利用每份检索报告的参考文献、综述文章、社论、研究生课程大纲和教科书进行了手工检索。在随后的综述中,使用分级量表对证据进行评估,其中随机对照试验最为重要。仅当从这些研究中获得独特数据时,才纳入在全国会议上发表的摘要。

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