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心理社会应激诱导的心率反应性与动脉粥样硬化:因果关系还是相关性?

Psychosocial stress-induced heart rate reactivity and atherogenesis: cause or correlation?

作者信息

Sharpley C F

机构信息

Department of Psychology, Bond University, Gold Coast, Queensland, Australia.

出版信息

J Behav Med. 1998 Oct;21(5):411-32. doi: 10.1023/a:1018734925282.

Abstract

The relationship between heart rate reactivity and atherogenesis is examined. Data from empirical studies are presented which support theoretical suggestions that it is the heart rate itself rather than the increase in heart rate following the onset of a stressor which is causally related to the development of arterial atherosclerosis. Several directions for research which will clarify this issue are discussed, with recent developments in the detection of atherosclerosis suggested as forming the basis of more reliable investigation of the effects of cardiac output variables upon arterial atherogenesis.

摘要

研究了心率反应性与动脉粥样硬化形成之间的关系。文中呈现了实证研究的数据,这些数据支持了理论观点,即与动脉粥样硬化发展存在因果关系的是心率本身,而非应激源出现后心率的增加。讨论了几个将阐明该问题的研究方向,并指出动脉粥样硬化检测方面的最新进展可作为更可靠地研究心输出量变量对动脉粥样硬化形成影响的基础。

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