Iwamoto I, Yonekawa S, Takeda T, Sakaguchi M, Ohno T, Tanaka H, Hasegawa H, Imada A, Horiuchi A, Umekawa T, Kurita T
Third Department of Internal Medicine, Kinki University School of Medicine, Osaka, Japan.
Am J Nephrol. 1998;18(6):534-7. doi: 10.1159/000013401.
Rapidly progressive glomerulonephritis was observed in a 37-year-old woman following the administration of extracorporeal shock wave lithotripsy (ESWL) for a single stone in her right kidney. The renal biopsy specimen showed diffuse cellular crescents in all glomeruli, with linear deposits of immunoglobulin G and complement component C3 along the glomerular basement membrane (GBM). Circulating anti-GBM antibodies were detected by enzyme-linked immunosorbent assay. Thus, the patient was diagnosed with anti-GBM nephritis. It is suggested that ESWL produced an alteration in the GBM leading to the production of anti-GBM antibodies.
一名37岁女性在接受体外冲击波碎石术（ESWL）治疗右肾单个结石后，出现了快速进展性肾小球肾炎。肾活检标本显示所有肾小球均有弥漫性细胞性新月体形成，免疫球蛋白G和补体成分C3沿肾小球基底膜（GBM）呈线性沉积。通过酶联免疫吸附测定法检测到循环抗GBM抗体。因此，该患者被诊断为抗GBM肾炎。提示ESWL导致GBM发生改变，从而产生抗GBM抗体。
