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慢性红斑狼疮的血管变化。电子显微镜研究。

Vascular changes of chronic lupus erythematosus. Electron microscopic studies.

作者信息

Kozakiewicz J, Wrzolkowa T

出版信息

Arch Dermatol Res (1975). 1976 Oct 27;256(3):327-31. doi: 10.1007/BF00572499.

DOI:10.1007/BF00572499
PMID:984884
Abstract

Vascular changes in the course of chronic lupus erythematosus were mainly characterized by a large, yet varying degree of proliferation of endothelial cells. In all cases examined the presence of tubular forms similar to paramyxoviruses was noted. The vascular basal membrane was noted to be either widened, segmentally separated or absent in places. Collagen fibres in these cases adhered directly to the endothelial cells. In the nuclei of endothelial cells of the infiltrate, "nuclear bodies" could be observed. In area surrounding capillaries oval concentrations of fibrilles 80 A in diameter were noticed.

摘要

慢性红斑狼疮病程中的血管变化主要表现为内皮细胞大量增生,但程度各异。在所有检查病例中,均发现存在类似于副粘病毒的管状结构。血管基底膜可见增宽、节段性分离或局部缺失。在这些病例中,胶原纤维直接附着于内皮细胞。在浸润灶的内皮细胞核中,可观察到“核体”。在毛细血管周围区域,注意到有直径80埃的纤维椭圆形聚集物。

相似文献

1
Vascular changes of chronic lupus erythematosus. Electron microscopic studies.慢性红斑狼疮的血管变化。电子显微镜研究。
Arch Dermatol Res (1975). 1976 Oct 27;256(3):327-31. doi: 10.1007/BF00572499.
2
[Tubular structures in affected and apparently normal kidneys in chronic discoid and systemic lupus erythematosus. An electron microscopic study (author's transl)].
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3
[Electron-microscopic studies of the mouth mucosa for the presence of virus-like particles in lupus erythematosus].[对红斑狼疮患者口腔黏膜进行电子显微镜检查以寻找病毒样颗粒]
Przegl Dermatol. 1980 Jan-Feb;67(1):9-18.
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Zentralbl Allg Pathol. 1974;118(5):452-62.
5
[Unusual nuclear inclusions in lymphocytes and basal cells of the skin in lupus erythematosus].
Dermatologica. 1973;146(2):132-7.
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Discoid lupus erythematosus. Electron microscopic studies of paramyxovirus-like structures.盘状红斑狼疮。副粘病毒样结构的电子显微镜研究。
Arch Dermatol. 1970 May;101(5):565-7. doi: 10.1001/archderm.101.5.565.
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Tubular structures in affected and normal skin in chronic discoid and systemic lupus erythematosus: electron microscopic studies.慢性盘状红斑狼疮和系统性红斑狼疮中受累皮肤及正常皮肤的管状结构:电子显微镜研究
Br J Dermatol. 1973 Jul;89(1):1-13. doi: 10.1111/j.1365-2133.1973.tb01909.x.
8
Ultrastructure of cutaneous lesions in lupus erythematosus: a comparison between the cutaneous and systemic types. (1) The basal lamina at the dermal-epidermal junction.红斑狼疮皮肤损害的超微结构:皮肤型与系统型的比较。(1) 真皮-表皮交界处的基底膜。
J Dermatol. 1981 Jun;8(3):175-86. doi: 10.1111/j.1346-8138.1981.tb02532.x.
9
[Lupus erythematosus profundus: two cases with ultrastructural study].
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Tubuloreticular inclusions in neonatal lupus erythematosus.新生儿红斑狼疮中的管网状包涵体。
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本文引用的文献

1
Discoid lupus erythematosus. Electron microscopic studies of paramyxovirus-like structures.盘状红斑狼疮。副粘病毒样结构的电子显微镜研究。
Arch Dermatol. 1970 May;101(5):565-7. doi: 10.1001/archderm.101.5.565.
2
Ultrastructure of dermal lesions in systemic lupus erythematosus.系统性红斑狼疮皮肤损害的超微结构
Lab Invest. 1970 Mar;22(3):189-97.
3
Comparison of the microangiopathy of systemic lupus erythematosus, dermatomyositis, scleroderma, and diabetes mellitus.系统性红斑狼疮、皮肌炎、硬皮病和糖尿病微血管病变的比较。
Lab Invest. 1970 Apr;22(4):301-8.
4
Tubular arrays in the endoplasmic reticulum in human tumor cells.人类肿瘤细胞内质网中的管状阵列
Lab Invest. 1971 Jun;24(6):492-8.
5
Endothelial inclusions in active lesions of systemic lupus erythematosus.系统性红斑狼疮活动病变中的内皮细胞包涵体。
J Lab Clin Med. 1969 Sep;74(3):369-79.
6
[Vascular lesions in the course of secondary syphilis in the light of histological and electron microscopic studies].[基于组织学和电子显微镜研究的二期梅毒病程中的血管病变]
Przegl Dermatol. 1974 Jul-Aug;61(4):449-56.
7
[Virus-like endoplasmatic structures in lupus erythematosus and in various other diseases of unknown etiology].[红斑狼疮及其他多种病因不明疾病中的病毒样内质网结构]
Hautarzt. 1973 Mar;24(3):95-105.
8
[Electron microscopy studies on the viral pathogenesis of lupus erythematosus].
Dermatol Monatsschr. 1972 Jul;158(7):485-91.
9
Ultrastructure of immune deposits in renal glomeruli.肾小球免疫沉积物的超微结构
Ann Intern Med. 1972 Mar;76(3):479-86. doi: 10.7326/0003-4819-76-3-479.
10
[Virus-like tubular formations detected in skin lesions in lupus erythematosus (electron microscope examinations)].
Przegl Dermatol. 1972 Jan-Feb;59(1):1-8.