Scott C S, Decker J L, Edwards M L, Freid E B
Division of Pharmacotherapy, School of Pharmacy, University of North Carolina at Chapel Hill, 27599-7360, USA.
Pharmacotherapy. 1998 Nov-Dec;18(6):1308-12.
Pharmacists at the 1995 American College of Clinical Pharmacy Pediatric Practice and Research Network meeting volunteered to act as coordinators at their sites and survey pediatric and neonatal nurses, pharmacists, and physicians regarding dependency in neonatal and pediatric patients after therapeutic administration of narcotics. Thirteen (60%) of 21 coordinators returned 244 surveys. Primary symptoms of withdrawal reported by clinicians were agitation (100%), irritability (100%), inconsolability (100%), crying (99%), tremors (98%), high heart rate (98%), fidgets (98%), high blood pressure (97%), less sleep (96%), and sweating (94%). Most clinicians considered narcotic withdrawal to be a problem (74%) that should be treated (87%). A dependency scale is being developed and will include symptoms reported by more than 75% of respondents.
在1995年美国临床药学学院儿科实践与研究网络会议上,药剂师们自愿在各自所在机构担任协调员,并就麻醉药品治疗性给药后新生儿和儿科患者的依赖性问题,对儿科和新生儿护士、药剂师及医生展开调查。21名协调员中有13名(60%)返回了244份调查问卷。临床医生报告的戒断主要症状有烦躁不安(100%)、易怒(100%)、无法安抚(100%)、哭闹(99%)、震颤(98%)、心率加快(98%)、坐立不安(98%)、血压升高(97%)、睡眠减少(96%)以及出汗(94%)。大多数临床医生认为麻醉药品戒断是一个问题(74%),且应该进行治疗(87%)。目前正在制定一个依赖性量表,该量表将纳入超过75%的受访者报告的症状。