假定的抑癌基因TP73的精确染色体定位
Refined chromosomal localization of the putative tumor suppressor gene TP73.
作者信息
Lo Cunsolo C, Casciano I, Banelli B, Tonini G P, Romani M
机构信息
Solid Tumor Biology Unit, Advanced Biotechnology Center (CBA), Genova (Italy).
出版信息
Cytogenet Cell Genet. 1998;82(3-4):199-201. doi: 10.1159/000015099.
PMID:9858816
Abstract
We report the refined chromosomal localization of the putative tumor suppressor gene TP73 (alias p73) within the genomic region between the anonymous loci D1Z2 and D1S47. The region measures less than 6 Mb and covers a genetic distance of 16 cM. The present mapping considerably restricts the previous cytogenetic localization of TP73.
摘要
我们报告了假定的肿瘤抑制基因TP73（别名p73）在无名基因座D1Z2和D1S47之间基因组区域内的精确染色体定位。该区域长度小于6兆碱基对，覆盖16厘摩的遗传距离。目前的定位大大缩小了之前TP73的细胞遗传学定位范围。
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