Frol'kis V V, Verkhrats'kyĭ N S, Myhovan S A, Dubileĭ T O, Rushkevych Iu Ie
Institute of Gerontology, Academy of Medical Sciences of Ukraine, Kiev.
Fiziol Zh (1994). 1998;44(5-6):7-13.
In rat experiments a new model of situational chronic stress, with the use of multicomponent natural stimulating influences, has been elaborated. The study revealed two subpopulations with longer and shorter lifespan in the group of stressed rats vs. control group. The survival of stressed animals was correspondent with the changes of adaptive indices. Thus the situational chronic stress has the geropromotive or geroprotective effect which depends on the organism's adaptive capacities.
在大鼠实验中,已构建出一种利用多组分自然刺激影响的情境性慢性应激新模型。研究发现,与对照组相比,应激大鼠组存在寿命较长和较短的两个亚群。应激动物的存活情况与适应性指标的变化相对应。因此,情境性慢性应激具有促衰老或抗衰老作用,这取决于机体的适应能力。