Figueredo Ruiz M, Fundora Sarraff T, Pérez Mora L, Ferrer Semanat R
Instituto de Hematología Inmunología, Ciudad de la Habana, Cuba.
Sangre (Barc). 1998 Oct;43(5):349-55.
To assess the blood volume (BV) of children by using different prediction formulas (PF) and to confirm the value of these in providing reference estimates.
The results of BV measurements in 19 children, performed at the Department of Physiology of the Haematology and Immunology Institute, were studied. The children had been sent to this centre to define the diagnosis of anaemia (11 cases) or polycythaemia (8 cases). Four adult and 2 children formulas based on body measurements were applied in order to estimate the reference BV. The relationship between the measured red cell volume (RCV) and plasma volume (PV) and the reference values was calculated for each formula, and the results were evaluated by establishing the normality criteria.
The PF used provided reference estimates of the different BV for a given patient. It was found that most adult formulas gave RCV and PV estimates which differ from those of children. PV was commonly decreased with all the formulas.
The different PF provide distinct BV estimates in most patients, and coincidentally the results differ in any given child. The formulas applied to adults, based on weight and height or body surface, should not be applied to estimate the BV in children. The use of equations based on height is recommended, correlating the BV assessment with the results of other studies.
通过使用不同的预测公式（PF）评估儿童的血容量（BV），并确认这些公式在提供参考估计值方面的价值。
研究了血液学与免疫学研究所生理学系对19名儿童进行的BV测量结果。这些儿童被送到该中心以明确贫血（11例）或红细胞增多症（8例）的诊断。应用了基于身体测量的4个成人公式和2个儿童公式来估计参考BV。计算每个公式测量的红细胞体积（RCV）和血浆体积（PV）与参考值之间的关系，并通过建立正态性标准对结果进行评估。
所使用的PF为给定患者提供了不同BV的参考估计值。发现大多数成人公式给出的RCV和PV估计值与儿童的不同。所有公式普遍使PV降低。
不同的PF在大多数患者中提供了不同的BV估计值，并且在任何给定儿童中结果也不同。基于体重、身高或体表面积的适用于成人的公式不适用于估计儿童的BV。建议使用基于身高的公式，将BV评估结果与其他研究结果相关联。
