Lekakis J, Papamichael C, Mavrikakis M, Voutsas A, Stamatelopoulos S
Department of Clinical Therapeutics, Athens University, Alexandra Hospital, Greece.
Am J Cardiol. 1998 Dec 15;82(12):1555-7, A8. doi: 10.1016/s0002-9149(98)00708-5.
Endothelium-dependent and endothelium-independent dilation were reduced in patients with Raynaud's phenomenon secondary to systemic sclerosis. Conjugated estrogen given for 4 weeks significantly improved endothelial function compared with placebo.