Waldhäusl W
Universitätsklinik für Innere Medizin III, Wien.
Acta Med Austriaca. 1998;25(4-5):113-6.
Precise regulation of food intake, both quantitatively and qualitatively, is required to provide for balanced energy supply and stable body weight in mammals as well as humans. These effects are of tantamount importance as any major deviation in body weight results either in impaired function due to reduced energy supply (underweight) or in system damage (overweight; metabolic syndrome). Regulation of food intake therefore is subject to a multitude of sensoric, neural and humoral control mechanisms informing on the actual state of energy supply as well as prevailing energy demand. The large number of control systems, however, provides also an opportunity for the development of multiple defects as potential causes of eating disorders. Their appropriate treatment will become accessible only with even more detailed knowledge than presently available, which is to provide the basis for correct diagnosis of eating disorders.
在哺乳动物和人类中，为了实现能量供应平衡和体重稳定，需要对食物摄入量在数量和质量上进行精确调节。这些影响至关重要，因为体重的任何重大偏差都会导致能量供应减少（体重过轻）引起的功能受损，或者导致系统损害（体重过重；代谢综合征）。因此，食物摄入量的调节受到多种感觉、神经和体液控制机制的影响，这些机制能够反映能量供应的实际状态以及当前的能量需求。然而，大量的控制系统也为多种缺陷的发展提供了机会，这些缺陷可能是饮食失调的潜在原因。只有获得比目前更详细的知识，才能进行适当的治疗，这将为饮食失调的正确诊断提供基础。
