儿童与青少年精神药理学。重要的发育问题。

Child and adolescent psychopharmacology. Important developmental issues.

作者信息

Tosyali M C, Greenhill L L

机构信息

Department of Child and Adolescent Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, USA.

出版信息

Pediatr Clin North Am. 1998 Oct;45(5):1021-35, vii. doi: 10.1016/s0031-3955(05)70060-2.

DOI:10.1016/s0031-3955(05)70060-2

PMID:9884673

Abstract

This article begins with an overview of developmental variations in pharmacokinetics and pharmacodynamics and then discusses issues related to decision making before beginning treatment with medication, including diagnosis, impairment, and consent. Subsequently, specific disorders, such as attention deficit hyperactivity disorder, mood disorders, and obsessive-compulsive disorder, are briefly discussed, with focus on issues relevant to a developmental approach to pediatric psychopharmacology.

摘要

本文首先概述了药代动力学和药效学的发育差异，然后讨论了在开始药物治疗前与决策相关的问题，包括诊断、损伤和同意。随后，简要讨论了特定疾病，如注意力缺陷多动障碍、情绪障碍和强迫症，重点关注与儿科精神药理学发育方法相关的问题。