Fedotenko S P, Uvarov A A
N.N. Blokhin Center for Cancer Research, Russian Academy of Medical Sciences, Moscow.
Vopr Onkol. 1998;44(5):569-72.
The experience of surgical treatment of residual tumor or recurrent carcinoma of the oral cavity at different stages after high-dose (more than 50 Gy) radiotherapy makes a case for wider application of surgery in cases that would be otherwise thought hopeless. Although the overall frequency of local postoperative complications is still high, the use of arterialized myocutaneous or adipose-cutaneous flaps during one-stage reconstructive surgery and effective postoperative management can provide a means to cut down the incidence of such grave complications as acute necrosis of tissues leading to hazardous bleeding and development of extensive defects of mandibular tissues and orostomas. More effort should be made to evolve procedures of surgical treatment to be given after high-dose radiotherapy.