Isu T, Tashiro K, Mitsumori K, Sato M, Tsuru M
No Shinkei Geka. 1976 Sep;4(9):897-901.
A rare case of intramedullary schwannoma of the spinal cord has been reported, The patient was a 30-year-old woman, who began to notice weakness in her right leg approximately 6 months prior to admission, followed 4 months later by numbness and weakness of the right arm. The above symptoms were progressively getting worse, and she was admitted to Hokkaido University Hospital on February 23, 1974. Neurological examination revealed slow speech, bilateral horizontal nystagmus, absent gag reflex and weakness of right trapezius muscle. Spasticity was noted in 4 extremities, in addition to right hemiparesis. All deep tendon reflexes were hyperactive, right more than left, with bilateral Hoffmann's and Babinski's signs. Vibration sense was diminished below the level of bilateral iliac crests. A tumor around the foramen magnum was suspected, however plain skull and neck, laminogram of cervical spines, vertebral arteriogram, fractional pneumoencephalogram and myodil myelogram failed to disclose abnormalities. Manometric Queckenstedt test showed a partial block on flexion, with CSF protein of 56 mg/dl. Air myelogram clearly visualized the presence of an intramedullary tumor at the level of the medullo-spinal junction. Subtotal removal of the intramedullary tumor at C1 was performed, which proved to be a schwannoma histologically. 14 such cases are reported in the literature and summarized on Table I, including our case. Clinical features of tumors around the foramen magnum are fairly complexed, and some radiological examinations might not be conclusive. It is stressed that air myelogram is extremely valuable in the diagnosis of lesions around the foramen magnum.
已报告一例罕见的脊髓髓内神经鞘瘤。患者为一名30岁女性,入院前约6个月开始注意到右腿无力,4个月后又出现右臂麻木和无力。上述症状逐渐加重,她于1974年2月23日入住北海道大学医院。神经学检查发现患者语速缓慢、双侧水平性眼球震颤、咽反射消失以及右斜方肌无力。除右半身轻瘫外,四肢均有痉挛。所有深腱反射亢进,右侧比左侧更明显,双侧出现霍夫曼征和巴宾斯基征。双侧髂嵴水平以下振动觉减退。怀疑枕骨大孔周围有肿瘤,然而,头颅和颈部平片、颈椎正位片、椎动脉造影、部分气脑造影和碘苯酯脊髓造影均未发现异常。压颈试验显示屈曲时部分梗阻,脑脊液蛋白为56mg/dl。气脑脊髓造影清楚地显示在延髓脊髓交界处水平存在髓内肿瘤。对C1水平的髓内肿瘤进行了次全切除,组织学检查证实为神经鞘瘤。文献中报告了14例此类病例,并汇总于表I,包括我们的病例。枕骨大孔周围肿瘤的临床特征相当复杂,一些放射学检查可能无法得出结论。强调气脑脊髓造影在枕骨大孔周围病变的诊断中具有极高的价值。