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在颈动脉注射异戊巴比妥钠试验期间记忆和语言功能的独立恢复。

Independent recovery of memory and language functioning during the Intracarotid Sodium Amytal Test.

作者信息

Morris R G, Polkey C E, Cox T

机构信息

Department of Clinical Psychology, Institute of Psychiatry, London, UK.

出版信息

J Clin Exp Neuropsychol. 1998 Aug;20(4):433-44. doi: 10.1076/jcen.20.4.433.1467.

Abstract

Memory and language recovery during the Intracarotid Sodium Amytal Test (IAP) was investigated in 49 left-hemisphere-dominant patients with unilateral temporal epileptic seizure foci. Memory was assessed by presenting items (words, objects, and faces) immediately after injection, and testing for recognition memory 10 min after motoric recovery. To assess language the patients responded verbally to the same items during memory presentation. Memory for the individual items was found to be independent of their presentation order and language functioning was impaired only with the dominant-hemisphere injection, recovering during the presentation of the memory items. These results suggest that the encoding of material remains at a constant level throughout the initial active phase of the IAP, whereas language functioning recovers independently.

摘要

在49例左侧半球优势、患有单侧颞叶癫痫发作灶的患者中,研究了颈动脉内注射异戊巴比妥钠试验(IAP)期间的记忆和语言恢复情况。通过在注射后立即呈现物品(单词、物体和面孔)来评估记忆,并在运动功能恢复10分钟后测试识别记忆。为了评估语言能力,患者在记忆呈现过程中对相同物品进行口头回答。发现单个物品的记忆与它们的呈现顺序无关,并且仅在优势半球注射时语言功能受损,在记忆物品呈现期间恢复。这些结果表明,在IAP的初始活跃阶段,材料的编码保持在恒定水平,而语言功能则独立恢复。

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