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[内耳积水时内淋巴管和内淋巴囊的病理学]

[Pathology of the endolymphatic duct and sac in inner-ear hydrops].

作者信息

Zechner G

出版信息

Arch Otorhinolaryngol. 1976 Sep 16;212(4):277-86. doi: 10.1007/BF00453675.

Abstract

The morphological substrate of Menière's disease is the endolymphatic hydrops. That can be idiopathic or secondary as a sequence of a labyrinthine disease of another cause. It is possible to coordinate function loss of the sensory end-organs and pathohistological findings, but not all failures are light-microscopically explainable. The reason for the hydrops is certainly a disturbance in the endolymph physiology. For the pathogenesis are important, besides the biochemistry of the inner ear-fluids, problems of the membranes and pathological changes on ductus and saccus endolymphaticus and perimacular areals and plana semilunata. The perilymphatic space, documentated on the example of the secondary hydrops, is certainly not only passively enrolled in the procedure. All observations bring the initiation and periodicity of attacks to another point of view. A complete solution has not been possible so far, especially in the case of the etiology in idiopathic hydrops.

摘要

梅尼埃病的形态学基础是内淋巴积水。其可为特发性的,或继发于其他病因的迷路疾病。感觉终器的功能丧失与病理组织学发现之间具有相关性,但并非所有功能丧失都能通过光学显微镜解释。积水的原因肯定是内淋巴生理紊乱。除内耳液的生物化学外,膜的问题、内淋巴管和球囊以及黄斑周围区域和半月形平面的病理变化对发病机制也很重要。以外淋巴积水为例,外淋巴间隙肯定不仅仅是被动地参与这一过程。所有观察结果都使人们对发作的起始和周期性有了新的认识。到目前为止,尚未找到完整的解决方案,尤其是在特发性积水的病因方面。

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